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Targeted Repolarization of Tumor‐Associated Macrophages via Imidazoquinoline‐Linked Nanobodies

Tumor‐associated macrophages (TAMs) promote the immune suppressive microenvironment inside tumors and are, therefore, considered as a promising target for the next generation of cancer immunotherapies. To repolarize their phenotype into a tumoricidal state, the Toll‐like receptor 7/8 agonist imidazo...

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Detalles Bibliográficos
Autores principales: Bolli, Evangelia, Scherger, Maximilian, Arnouk, Sana M., Pombo Antunes, Ana Rita, Straßburger, David, Urschbach, Moritz, Stickdorn, Judith, De Vlaminck, Karen, Movahedi, Kiavash, Räder, Hans Joachim, Hernot, Sophie, Besenius, Pol, Van Ginderachter, Jo A., Nuhn, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132149/
https://www.ncbi.nlm.nih.gov/pubmed/34026453
http://dx.doi.org/10.1002/advs.202004574