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PRMT5 Enables Robust STAT3 Activation via Arginine Symmetric Dimethylation of SMAD7

Protein arginine methyltransferase 5 (PRMT5) is the type II arginine methyltransferase that catalyzes the mono‐ and symmetrical dimethylation of protein substrates at the arginine residues. Emerging evidence reveals that PRMT5 is involved in the regulation of tumor cell proliferation and cancer deve...

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Detalles Bibliográficos
Autores principales: Cai, Congcong, Gu, Shuchen, Yu, Yi, Zhu, Yezhang, Zhang, HanChenxi, Yuan, Bo, Shen, Li, Yang, Bing, Feng, Xin‐Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132155/
https://www.ncbi.nlm.nih.gov/pubmed/34026434
http://dx.doi.org/10.1002/advs.202003047