Impaired immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19

Secondary bacterial infections, including ventilator-associated pneumonia (VAP), lead to worse clinical outcomes and increased mortality following viral respiratory infections including in patients with coronavirus disease 2019 (COVID-19). Using a combination of tracheal aspirate bulk and single-cel...

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Detalles Bibliográficos
Autores principales: Tsitsiklis, Alexandra, Zha, Beth Shoshana, Byrne, Ashley, Devoe, Catherine, Levan, Sophia, Rackaityte, Elze, Sunshine, Sara, Mick, Eran, Ghale, Rajani, Jauregui, Alejandra, Sarma, Aartik, Neff, Norma, Serpa, Paula Hayakawa, Deiss, Thomas J., Kistler, Amy, Carrillo, Sidney, Ansel, K. Mark, Leligdowicz, Aleksandra, Christenson, Stephanie, Jones, Norman, Wu, Bing, Darmanis, Spyros, Matthay, Michael A., Lynch, Susan V., DeRisi, Joseph L., Hendrickson, Carolyn M., Kangelaris, Kirsten N., Krummel, Matthew F., Woodruff, Prescott G., Erle, David J., Rosenberg, Oren, Calfee, Carolyn S., Langelier, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132240/
https://www.ncbi.nlm.nih.gov/pubmed/34013247
http://dx.doi.org/10.21203/rs.3.rs-380803/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132240/
https://www.ncbi.nlm.nih.gov/pubmed/34013247
http://dx.doi.org/10.21203/rs.3.rs-380803/v1

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