The small-molecule protein ligand interface stabiliser E7820 induces differential cell line specific responses of integrin α2 expression

BACKGROUND: The mechanism of small-molecule stabilised protein-protein interactions is of growing interest in the pharmacological discovery process. A plethora of different substances including the aromatic sulphonamide E7820 have been identified to act by such a mechanism. The process of E7820 indu...

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Detalles Bibliográficos
Autores principales: Hülskamp, Michael David, Kronenberg, Daniel, Stange, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132423/
https://www.ncbi.nlm.nih.gov/pubmed/34006252
http://dx.doi.org/10.1186/s12885-021-08301-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132423/
https://www.ncbi.nlm.nih.gov/pubmed/34006252
http://dx.doi.org/10.1186/s12885-021-08301-w

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