Cargando…
The small-molecule protein ligand interface stabiliser E7820 induces differential cell line specific responses of integrin α2 expression
BACKGROUND: The mechanism of small-molecule stabilised protein-protein interactions is of growing interest in the pharmacological discovery process. A plethora of different substances including the aromatic sulphonamide E7820 have been identified to act by such a mechanism. The process of E7820 indu...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132423/ https://www.ncbi.nlm.nih.gov/pubmed/34006252 http://dx.doi.org/10.1186/s12885-021-08301-w |