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Determination of equi-analgesic doses of inhaled methoxyflurane versus intravenous fentanyl using the cold pressor test in volunteers: a randomised, double-blinded, placebo-controlled crossover study

BACKGROUND: Inhaled methoxyflurane for acute pain relief has demonstrated an analgesic effect superior to placebo. Data comparing methoxyflurane to an opioid are needed. The aim of this study was to determine the equi-analgesic doses of inhaled methoxyflurane vs i.v. fentanyl. Both drugs have an ons...

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Detalles Bibliográficos
Autores principales: Lenz, Harald, Høiseth, Lars Ø., Comelon, Marlin, Draegni, Tomas, Rosseland, Leiv A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132882/
https://www.ncbi.nlm.nih.gov/pubmed/33676727
http://dx.doi.org/10.1016/j.bja.2020.12.045