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A synthetic pathogen mimetic molecule induces a highly amplified synergistic immune response via activation of multiple signaling pathways

The current understanding of how the immune system processes complex information during natural infections is yet to be exploited for the molecular design of potent immune activators. Here, we address this challenge by design of a pathogen-mimetic molecule that simultaneously co-activates cell-surfa...

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Detalles Bibliográficos
Autores principales: Nihesh, Naorem, Manna, Saikat, Studnitzer, Bradley, Shen, Jingjing, Esser-Kahn, Aaron P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132936/
https://www.ncbi.nlm.nih.gov/pubmed/34040739
http://dx.doi.org/10.1039/d1sc00964h