Isothiourea-catalysed enantioselective Michael addition of N-heterocyclic pronucleophiles to α,β-unsaturated aryl esters

The isothiourea-catalysed enantioselective Michael addition of 3-aryloxindole and 4-substituted-dihydropyrazol-3-one pronucleophiles to α,β-unsaturated p-nitrophenyl esters is reported. This process generates products containing two contiguous stereocentres, one quaternary, in good yields and excell...

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Detalles Bibliográficos
Autores principales: Shu, Chang, Liu, Honglei, Slawin, Alexandra M. Z., Carpenter-Warren, Cameron, Smith, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133005/
https://www.ncbi.nlm.nih.gov/pubmed/34040717
http://dx.doi.org/10.1039/c9sc04303a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133005/
https://www.ncbi.nlm.nih.gov/pubmed/34040717
http://dx.doi.org/10.1039/c9sc04303a

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