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The Antifungal Activity of HMA, an Amiloride Analog and Inhibitor of Na(+)/H(+) Exchangers
One path toward identifying effective and easily accessible antifungals is to repurpose commonly used drugs. Amiloride, a widely used diuretic, inhibits different isoforms of Na(+)/H(+) exchangers, Na(+) channels, and Na(+)/Ca(2+) exchangers. Here, we found that amiloride had poor antifungal activit...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133316/ https://www.ncbi.nlm.nih.gov/pubmed/34025629 http://dx.doi.org/10.3389/fmicb.2021.673035 |