Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies

Antibodies that target the glycan cap epitope on the ebolavirus glycoprotein (GP) are common in the adaptive response of survivors. A subset is known to be broadly neutralizing, but the details of their epitopes and basis for neutralization are not well understood. Here, we present cryoelectron micr...

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Detalles Bibliográficos
Autores principales: Murin, Charles D., Gilchuk, Pavlo, Ilinykh, Philipp A., Huang, Kai, Kuzmina, Natalia, Shen, Xiaoli, Bruhn, Jessica F., Bryan, Aubrey L., Davidson, Edgar, Doranz, Benjamin J., Williamson, Lauren E., Copps, Jeffrey, Alkutkar, Tanwee, Flyak, Andrew I., Bukreyev, Alexander, Crowe, James E., Ward, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133395/
https://www.ncbi.nlm.nih.gov/pubmed/33852862
http://dx.doi.org/10.1016/j.celrep.2021.108984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133395/
https://www.ncbi.nlm.nih.gov/pubmed/33852862
http://dx.doi.org/10.1016/j.celrep.2021.108984

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