SARS-CoV-2 infection induces beta cell transdifferentiation

Recent clinical data have suggested a correlation between coronavirus disease 2019 (COVID-19) and diabetes. Here, we describe the detection of SARS-CoV-2 viral antigen in pancreatic beta cells in autopsy samples from individuals with COVID-19. Single-cell RNA sequencing and immunostaining from ex vi...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Xuming, Uhl, Skyler, Zhang, Tuo, Xue, Dongxiang, Li, Bo, Vandana, J. Jeya, Acklin, Joshua A., Bonnycastle, Lori L., Narisu, Narisu, Erdos, Michael R., Bram, Yaron, Chandar, Vasuretha, Chong, Angie Chi Nok, Lacko, Lauretta A., Min, Zaw, Lim, Jean K., Borczuk, Alain C., Xiang, Jenny, Naji, Ali, Collins, Francis S., Evans, Todd, Liu, Chengyang, tenOever, Benjamin R., Schwartz, Robert E., Chen, Shuibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Clinical and Translational Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133495/
https://www.ncbi.nlm.nih.gov/pubmed/34081913
http://dx.doi.org/10.1016/j.cmet.2021.05.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133495/
https://www.ncbi.nlm.nih.gov/pubmed/34081913
http://dx.doi.org/10.1016/j.cmet.2021.05.015

Ejemplares similares