Functional coordination of BET family proteins underlies altered transcription associated with memory impairment in fragile X syndrome

Bromodomain and extraterminal proteins (BET) are epigenetic readers that play critical roles in gene regulation. Pharmacologic inhibition of the bromodomain present in all BET family members is a promising therapeutic strategy for various diseases, but its impact on individual family members has not...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Seung-Kyoon, Liu, Xihui, Park, Jongmin, Um, Dahun, Kilaru, Gokhul, Chiang, Cheng-Ming, Kang, Mingon, Huber, Kimberly M., Kang, Keunsoo, Kim, Tae-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133748/
https://www.ncbi.nlm.nih.gov/pubmed/34138732
http://dx.doi.org/10.1126/sciadv.abf7346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133748/
https://www.ncbi.nlm.nih.gov/pubmed/34138732
http://dx.doi.org/10.1126/sciadv.abf7346

Ejemplares similares