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Targeting nucleotide metabolism as the nexus of viral infections, cancer, and the immune response

Virus-infected cells and cancers share metabolic commonalities that stem from their insatiable need to replicate while evading the host immune system. These similarities include hijacking signaling mechanisms that induce metabolic rewiring in the host to up-regulate nucleotide metabolism and, in par...

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Detalles Bibliográficos
Autores principales: Ariav, Yarden, Ch’ng, James H, Christofk, Heather R., Ron-Harel, Noga, Erez, Ayelet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133749/
https://www.ncbi.nlm.nih.gov/pubmed/34138729
http://dx.doi.org/10.1126/sciadv.abg6165