Reduced purine biosynthesis in humans after their divergence from Neandertals

We analyze the metabolomes of humans, chimpanzees, and macaques in muscle, kidney and three different regions of the brain. Although several compounds in amino acid metabolism occur at either higher or lower concentrations in humans than in the other primates, metabolites downstream of adenylosuccin...

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Detalles Bibliográficos
Autores principales: Stepanova, Vita, Moczulska, Kaja Ewa, Vacano, Guido N, Kurochkin, Ilia, Ju, Xiangchun, Riesenberg, Stephan, Macak, Dominik, Maricic, Tomislav, Dombrowski, Linda, Schörnig, Maria, Anastassiadis, Konstantinos, Baker, Oliver, Naumann, Ronald, Khrameeva, Ekaterina, Vanushkina, Anna, Stekolshchikova, Elena, Egorova, Alina, Tkachev, Anna, Mazzarino, Randall, Duval, Nathan, Zubkov, Dmitri, Giavalisco, Patrick, Wilkinson, Terry G, Patterson, David, Khaitovich, Philipp, Pääbo, Svante
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133780/
https://www.ncbi.nlm.nih.gov/pubmed/33942714
http://dx.doi.org/10.7554/eLife.58741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133780/
https://www.ncbi.nlm.nih.gov/pubmed/33942714
http://dx.doi.org/10.7554/eLife.58741

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