Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation

Phospholipase D (PLD) is an enzyme useful for the enzymatic modification of phospholipids. In the presence of primary alcohols, the enzyme catalyses transphosphatidylation of the head group of phospholipid substrates to synthesise a modified phospholipid product. However, the enzyme is specific for...

Descripción completa

Detalles Bibliográficos
Autores principales: Samantha, Ariela, Damnjanović, Jasmina, Iwasaki, Yugo, Nakano, Hideo, Vrielink, Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133832/
https://www.ncbi.nlm.nih.gov/pubmed/33843991
http://dx.doi.org/10.1042/BCJ20210117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133832/
https://www.ncbi.nlm.nih.gov/pubmed/33843991
http://dx.doi.org/10.1042/BCJ20210117

Ejemplares similares