High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status

Clinical definitions of asthma fail to capture the heterogeneity of immune dysfunction in severe, treatment-refractory disease. Applying mass cytometry and machine learning to bronchoalveolar lavage (BAL) cells, we find that corticosteroid-resistant asthma patients cluster largely into two groups: o...

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Detalles Bibliográficos
Autores principales: Camiolo, Matthew J., Zhou, Xiaoying, Oriss, Timothy B., Yan, Qi, Gorry, Michael, Horne, William, Trudeau, John B., Scholl, Kathryn, Chen, Wei, Kolls, Jay K., Ray, Prabir, Weisel, Florian J., Weisel, Nadine M., Aghaeepour, Nima, Nadeau, Kari, Wenzel, Sally E., Ray, Anuradha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133874/
https://www.ncbi.nlm.nih.gov/pubmed/33852838
http://dx.doi.org/10.1016/j.celrep.2021.108974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133874/
https://www.ncbi.nlm.nih.gov/pubmed/33852838
http://dx.doi.org/10.1016/j.celrep.2021.108974

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