MRE11 promotes oral cancer progression through RUNX2/CXCR4/AKT/FOXA2 signaling in a nuclease-independent manner

MRE11, the nuclease component of RAD50/MRE11/NBS1 DNA repair complex which is essential for repair of DNA double-strand-breaks in normal cells, has recently garnered attention as a critical factor in solid tumor development. Herein we report the crucial role of MRE11 in oral cancer progression in a...

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Detalles Bibliográficos
Autores principales: Wang, Yen-Yun, Chen, Yuk-Kwan, Lo, Steven, Chi, Tsung-Chen, Chen, Yi-Hua, Hu, Stephen Chu-Sung, Chen, Ya-Wen, Jiang, Shih Sheng, Tsai, Fang-Yu, Liu, Wangta, Li, Ruei-Nian, Hsieh, Ya-Ching, Huang, Chih-Jen, Yuan, Shyng-Shiou F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134045/
https://www.ncbi.nlm.nih.gov/pubmed/33927349
http://dx.doi.org/10.1038/s41388-021-01698-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134045/
https://www.ncbi.nlm.nih.gov/pubmed/33927349
http://dx.doi.org/10.1038/s41388-021-01698-5

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