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Chronic cold exposure induces autophagy to promote fatty acid oxidation, mitochondrial turnover, and thermogenesis in brown adipose tissue

Autophagy plays an important role in lipid breakdown, mitochondrial turnover, and mitochondrial function during brown adipose tissue (BAT) activation by thyroid hormone, but its role in BAT during adaptive thermogenesis remains controversial. Here, we examined BAT from mice exposed to 72 h of cold c...

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Detalles Bibliográficos
Autores principales: Yau, Winifred W., Wong, Kiraely Adam, Zhou, Jin, Thimmukonda, Nivetha Kanakaram, Wu, Yajun, Bay, Boon-Huat, Singh, Brijesh Kumar, Yen, Paul Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134067/
https://www.ncbi.nlm.nih.gov/pubmed/34027318
http://dx.doi.org/10.1016/j.isci.2021.102434