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Conserved proline residues in the coiled coil–OB domain linkers of Rpt proteins facilitate eukaryotic proteasome base assembly

The proteasome is a large protease complex that degrades many different cellular proteins. In eukaryotes, the 26S proteasome contains six different subunits of the ATPases associated with diverse cellular activities family, Rpt1–Rpt6, which form a hexameric ring as part of the base subcomplex that d...

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Detalles Bibliográficos
Autores principales: Cheng, Chin Leng, Wong, Michael K., Li, Yanjie, Hochstrasser, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134078/
https://www.ncbi.nlm.nih.gov/pubmed/33862083
http://dx.doi.org/10.1016/j.jbc.2021.100660