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The prevalence of secondary neoplasms in acromegalic patients: possible preventive and/or protective role of metformin

BACKGROUND: Acromegaly is a rare disease due to chronic growth hormone (GH) excess and the consequent increase in insulin-like growth factor-1 (IGF-1) levels. Both GH and IGF-1 play a role in intermediate metabolism affecting glucose homeostasis. The association between hyperinsulinemia/impaired glu...

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Detalles Bibliográficos
Autores principales: Costa, Denise, Ceccato, Filippo, Lauretta, Rosa, Mercuri, Valeria, D’Amico, Tania, De Vito, Corrado, Scaroni, Carla, Appetecchia, Marialuisa, Gargiulo, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134278/
https://www.ncbi.nlm.nih.gov/pubmed/33713207
http://dx.doi.org/10.1007/s10147-021-01895-y