Feasibility of predicting allele specific expression from DNA sequencing using machine learning

Allele specific expression (ASE) concerns divergent expression quantity of alternative alleles and is measured by RNA sequencing. Multiple studies show that ASE plays a role in hereditary diseases by modulating penetrance or phenotype severity. However, genome diagnostics is based on DNA sequencing...

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Detalles Bibliográficos
Autores principales: Zhang, Zhenhua, van Dijk, Freerk, de Klein, Niek, van Gijn, Mariëlle E, Franke, Lude H, Sinke, Richard J, Swertz, Morris A, van der Velde, K Joeri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134421/
https://www.ncbi.nlm.nih.gov/pubmed/34012022
http://dx.doi.org/10.1038/s41598-021-89904-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134421/
https://www.ncbi.nlm.nih.gov/pubmed/34012022
http://dx.doi.org/10.1038/s41598-021-89904-y

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