Metalloproteinase 1 downregulation in neurofibromatosis 1: Therapeutic potential of antimalarial hydroxychloroquine and chloroquine

Neurofibromatosis type 1 is an autosomal dominant genetic disorder caused by mutation in the neurofibromin 1 (NF1) gene. Its hallmarks are cutaneous findings including neurofibromas, benign peripheral nerve sheath tumors. We analyzed the collagen and matrix metalloproteinase 1 (MMP1) expression in N...

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Detalles Bibliográficos
Autores principales: Tsuji, Gaku, Takai-Yumine, Ayako, Kato, Takahiro, Furue, Masutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134427/
https://www.ncbi.nlm.nih.gov/pubmed/34011935
http://dx.doi.org/10.1038/s41419-021-03802-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134427/
https://www.ncbi.nlm.nih.gov/pubmed/34011935
http://dx.doi.org/10.1038/s41419-021-03802-9

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