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MMP20-generated amelogenin cleavage products prevent formation of fan-shaped enamel malformations
Dental enamel forms extracellularly as thin ribbons of amorphous calcium phosphate (ACP) that initiate on dentin mineral in close proximity to the ameloblast distal membrane. Secreted proteins are critical for this process. Enam(−/−) and Ambn(−/−) mice fail to form enamel. We characterize enamel rib...
Autores principales: | Bartlett, John D., Smith, Charles E., Hu, Yuanyuan, Ikeda, Atsushi, Strauss, Mike, Liang, Tian, Hsu, Ya-Hsiang, Trout, Amanda H., McComb, David W., Freeman, Rebecca C., Simmer, James P., Hu, Jan C.-C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134442/ https://www.ncbi.nlm.nih.gov/pubmed/34012043 http://dx.doi.org/10.1038/s41598-021-90005-z |
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