Arylmethylene hydrazine derivatives containing 1,3-dimethylbarbituric moiety as novel urease inhibitors

A new series of arylmethylene hydrazine derivatives bearing 1,3-dimethylbarbituric moiety 7a–o were designed, synthesized, and evaluated for their in vitro urease inhibitory activity. All the title compounds displayed high anti-urease activity, with IC(50) values in the range of 0.61 ± 0.06–4.56 ± 0...

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Detalles Bibliográficos
Autores principales: Pedrood, Keyvan, Azizian, Homa, Montazer, Mohammad Nazari, Mohammadi‐Khanaposhtani, Maryam, Asgari, Mohammad Sadegh, Asadi, Mehdi, Bahadorikhalili, Saeed, Rastegar, Hossein, Larijani, Bagher, Amanlou, Massoud, Mahdavi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134453/
https://www.ncbi.nlm.nih.gov/pubmed/34012008
http://dx.doi.org/10.1038/s41598-021-90104-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134453/
https://www.ncbi.nlm.nih.gov/pubmed/34012008
http://dx.doi.org/10.1038/s41598-021-90104-x

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