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Assessment of select synthetic cannabinoid receptor agonist bias and selectivity between the type 1 and type 2 cannabinoid receptor

The first synthetic cannabinoid receptor agonists (SCRAs) were designed as tool compounds to study the endocannabinoid system’s two predominant cannabinoid receptors, CB1R and CB2R. Unfortunately, novel SCRAs now represent the most rapidly proliferating novel psychoactive substances (NPS) of abuse g...

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Detalles Bibliográficos
Autores principales: Zagzoog, Ayat, Brandt, Asher L., Black, Tallan, Kim, Eunhyun D., Burkart, Riley, Patel, Mikin, Jin, Zhiyun, Nikolaeva, Maria, Laprairie, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134483/
https://www.ncbi.nlm.nih.gov/pubmed/34012003
http://dx.doi.org/10.1038/s41598-021-90167-w