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Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders

Despite strong evidence of heritability and growing discovery of genetic markers for major mental illness, little is known about how gene expression in the brain differs across psychiatric diagnoses, or how known genetic risk factors shape these differences. Here we investigate expressed genes and g...

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Detalles Bibliográficos
Autores principales: Akula, Nirmala, Marenco, Stefano, Johnson, Kory, Feng, Ningping, Zhu, Kevin, Schulmann, Anton, Corona, Winston, Jiang, Xueying, Cross, Joanna, England, Bryce, Nathan, Aparna, Detera-Wadleigh, Sevilla, Xu, Qing, Auluck, Pavan K., An, Kwangmi, Kramer, Robin, Apud, Jose, Harris, Brent T., Harker Rhodes, C., Lipska, Barbara K., McMahon, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134494/
https://www.ncbi.nlm.nih.gov/pubmed/33558674
http://dx.doi.org/10.1038/s41386-020-00949-5