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Human delta like 1-expressing human mesenchymal stromal cells promote human T cell development and antigen-specific response in humanized NOD/SCID/IL-2R[Formula: see text] (null) (NSG) mice

Human delta-like 1 (hDlk1) is known to be able to regulate cell fate decisions during hematopoiesis. Mesenchymal stromal cells (MSCs) are known to exhibit potent immunomodulatory roles in a variety of diseases. Herein, we investigated in vivo functions of hDlk1(-)hMSCs and hDlk1(+)hMSCs in T cell de...

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Detalles Bibliográficos
Autores principales: Kwon, Do Hee, Park, Jae Berm, Lee, Joo Sang, Kim, Sung Joo, Choi, Bongkum, Lee, Ki-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134586/
https://www.ncbi.nlm.nih.gov/pubmed/34011992
http://dx.doi.org/10.1038/s41598-021-90110-z