Alternative polyadenylation trans-factor FIP1 exacerbates UUO/IRI-induced kidney injury and contributes to AKI-CKD transition via ROS-NLRP3 axis

NLRP3, a decisive role in inflammation regulation, is obviously upregulated by oxidative stress in kidney injury. The NLRP3 upregulation leads to unsolved inflammation and other pathological effects, contributing to aggravation of kidney injury and even transition to chronic kidney disease (CKD). Ho...

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Detalles Bibliográficos
Autores principales: Zheng, Tong, Tan, Yuqin, Qiu, Jiang, Xie, Zhenwei, Hu, Xiao, Zhang, Jinhua, Na, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134587/
https://www.ncbi.nlm.nih.gov/pubmed/34011928
http://dx.doi.org/10.1038/s41419-021-03751-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134587/
https://www.ncbi.nlm.nih.gov/pubmed/34011928
http://dx.doi.org/10.1038/s41419-021-03751-3

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