Hereditary Spastic Paraplegia and Future Therapeutic Directions: Beneficial Effects of Small Compounds Acting on Cellular Stress

Hereditary spastic paraplegia (HSP) is a group of inherited neurodegenerative conditions that share a characteristic feature of degeneration of the longest axons within the corticospinal tract, which leads to progressive spasticity and weakness of the lower limbs. Mutations of over 70 genes produce...

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Detalles Bibliográficos
Autores principales: Gumeni, Sentiljana, Vantaggiato, Chiara, Montopoli, Monica, Orso, Genny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134669/
https://www.ncbi.nlm.nih.gov/pubmed/34025345
http://dx.doi.org/10.3389/fnins.2021.660714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134669/
https://www.ncbi.nlm.nih.gov/pubmed/34025345
http://dx.doi.org/10.3389/fnins.2021.660714

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