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Hereditary Spastic Paraplegia and Future Therapeutic Directions: Beneficial Effects of Small Compounds Acting on Cellular Stress

Hereditary spastic paraplegia (HSP) is a group of inherited neurodegenerative conditions that share a characteristic feature of degeneration of the longest axons within the corticospinal tract, which leads to progressive spasticity and weakness of the lower limbs. Mutations of over 70 genes produce...

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Detalles Bibliográficos
Autores principales:	Gumeni, Sentiljana, Vantaggiato, Chiara, Montopoli, Monica, Orso, Genny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134669/ https://www.ncbi.nlm.nih.gov/pubmed/34025345 http://dx.doi.org/10.3389/fnins.2021.660714

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