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Acid Ceramidase Protects Against Hepatic Ischemia/Reperfusion Injury by Modulating Sphingolipid Metabolism and Reducing Inflammation and Oxidative Stress

Ceramide is a bioactive signaling lipid involved in the pathogenesis of numerous diseases. It also plays an important role in ischemia reperfusion (IR) injury via activation of inflammatory/oxidative stress-stimulated signaling pathways, resulting in tissue damage. Acid ceramidase is a lipid hydrola...

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Detalles Bibliográficos
Autores principales: Jiang, Yuan, He, Xingxuan, Simonaro, Calogera M., Yi, Bin, Schuchman, Edward H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134688/
https://www.ncbi.nlm.nih.gov/pubmed/34026750
http://dx.doi.org/10.3389/fcell.2021.633657