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WNT3A‐loaded exosomes enable cartilage repair

Cartilage defects repair poorly. Recent genetic studies suggest that WNT3a may contribute to cartilage regeneration, however the dense, avascular cartilage extracellular matrix limits its penetration and signalling to chondrocytes. Extracellular vesicles actively penetrate intact cartilage. This stu...

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Detalles Bibliográficos
Autores principales: Thomas, Bethan L., Eldridge, Suzanne E., Nosrati, Babak, Alvarez, Mario, Thorup, Anne‐Sophie, Nalesso, Giovanna, Caxaria, Sara, Barawi, Aida, Nicholson, James G., Perretti, Mauro, Gaston‐Massuet, Carles, Pitzalis, Costantino, Maloney, Alison, Moore, Adrian, Jupp, Ray, Dell'Accio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134720/
https://www.ncbi.nlm.nih.gov/pubmed/34025953
http://dx.doi.org/10.1002/jev2.12088