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WNT3A‐loaded exosomes enable cartilage repair
Cartilage defects repair poorly. Recent genetic studies suggest that WNT3a may contribute to cartilage regeneration, however the dense, avascular cartilage extracellular matrix limits its penetration and signalling to chondrocytes. Extracellular vesicles actively penetrate intact cartilage. This stu...
Autores principales: | Thomas, Bethan L., Eldridge, Suzanne E., Nosrati, Babak, Alvarez, Mario, Thorup, Anne‐Sophie, Nalesso, Giovanna, Caxaria, Sara, Barawi, Aida, Nicholson, James G., Perretti, Mauro, Gaston‐Massuet, Carles, Pitzalis, Costantino, Maloney, Alison, Moore, Adrian, Jupp, Ray, Dell'Accio, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134720/ https://www.ncbi.nlm.nih.gov/pubmed/34025953 http://dx.doi.org/10.1002/jev2.12088 |
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