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Ginseng gintonin alleviates neurological symptoms in the G93A-SOD1 transgenic mouse model of amyotrophic lateral sclerosis through lysophosphatidic acid 1 receptor

BACKGROUND: We recently showed that gintonin, an active ginseng ingredient, exhibits antibrain neurodegenerative disease effects including multiple target mechanisms such as antioxidative stress and antiinflammation via the lysophosphatidic acid (LPA) receptors. Amyotrophic lateral sclerosis (ALS) i...

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Detalles Bibliográficos
Autores principales: Nam, Sung Min, Choi, Jong Hee, Choi, Sun-Hye, Cho, Hee-Jung, Cho, Yeon-Jin, Rhim, Hyewhon, Kim, Hyoung-Chun, Cho, Ik-Hyun, Kim, Do-Geun, Nah, Seung-Yeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134849/
https://www.ncbi.nlm.nih.gov/pubmed/34025132
http://dx.doi.org/10.1016/j.jgr.2020.04.002