Saponins from Panax japonicus ameliorate age-related renal fibrosis by inhibition of inflammation mediated by NF-κB and TGF-β1/Smad signaling and suppression of oxidative stress via activation of Nrf2-ARE signaling

BACKGROUND: The decreased renal function is known to be associated with biological aging, of which the main pathological features are chronic inflammation and renal interstitial fibrosis. In previous studies, we reported that total saponins from Panax japonicus (SPJs) can availably protect acute myo...

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Detalles Bibliográficos
Autores principales: Gao, Yan, Yuan, Ding, Gai, Liyue, Wu, Xuelian, Shi, Yue, He, Yumin, Liu, Chaoqi, Zhang, Changcheng, Zhou, Gang, Yuan, Chengfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134850/
https://www.ncbi.nlm.nih.gov/pubmed/34025134
http://dx.doi.org/10.1016/j.jgr.2020.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134850/
https://www.ncbi.nlm.nih.gov/pubmed/34025134
http://dx.doi.org/10.1016/j.jgr.2020.08.005

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