Inflammation can increase hepcidin in HFE‐hereditary hemochromatosis

We present a p.C282Y homozygous patient with high hepcidin levels and normal iron parameters during systemic inflammation. This suggests that in the absence of a proper functioning HFE, resulting in blockage of the BMP/SMAD pathway, the innate low hepcidin concentration can be upregulated by inflamm...

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Detalles Bibliográficos
Autores principales: Moris, Wenke, Verhaegh, Pauline L. M., Masclee, Ad A. M., Swinkels, Dorine W., Laarakkers, Coby M., Koek, Ger H., van Deursen, Cees Th. B. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134951/
https://www.ncbi.nlm.nih.gov/pubmed/34026154
http://dx.doi.org/10.1002/ccr3.4114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134951/
https://www.ncbi.nlm.nih.gov/pubmed/34026154
http://dx.doi.org/10.1002/ccr3.4114

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