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Experimental virus evolution in cancer cell monolayers, spheroids, and tissue explants

Viral laboratory evolution has been used for different applications, such as modeling viral emergence, drug-resistance prediction, and therapeutic virus optimization. However, these studies have been mainly performed in cell monolayers, a highly simplified environment, raising concerns about their a...

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Detalles Bibliográficos
Autores principales: Al-Zaher, Ahmed, Domingo-Calap, Pilar, Sanjuán, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134955/
https://www.ncbi.nlm.nih.gov/pubmed/34040797
http://dx.doi.org/10.1093/ve/veab045