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Experimental virus evolution in cancer cell monolayers, spheroids, and tissue explants
Viral laboratory evolution has been used for different applications, such as modeling viral emergence, drug-resistance prediction, and therapeutic virus optimization. However, these studies have been mainly performed in cell monolayers, a highly simplified environment, raising concerns about their a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134955/ https://www.ncbi.nlm.nih.gov/pubmed/34040797 http://dx.doi.org/10.1093/ve/veab045 |