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Synthesis and evaluation of the in vitro and in vivo antitrypanosomal activity of 2-styrylquinolines

In this study, we report the synthesis and evaluation of in vitro and in vivo antitrypanosomal activity of styrylquinoline-like compounds (SQ) 3a-h. Synthesis was carried out by using quinaldine and 8- hydroxyquinaldine with a variety of aromatic aldehydes. The structure of SQs was corroborated by o...

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Detalles Bibliográficos
Autores principales: Espinosa, Roger, Robledo, Sara, Guzmán, Camilo, Arbeláez, Natalia, Yepes, Lina, Santafé, Gílmar, Sáez, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134988/
https://www.ncbi.nlm.nih.gov/pubmed/34036197
http://dx.doi.org/10.1016/j.heliyon.2021.e07024