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Trimethylamine modulates dauer formation, neurodegeneration, and lifespan through tyra‐3/daf‐11 signaling in Caenorhabditis elegans
In the nematode Caenorhabditis elegans, signals derived from bacteria in the diet, the animal's major nutrient source, can modulate both behavior and healthspan. Here we describe a dual role for trimethylamine (TMA), a human gut flora metabolite, which acts as a nutrient signal and a neurotoxin...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8135002/ https://www.ncbi.nlm.nih.gov/pubmed/33819374 http://dx.doi.org/10.1111/acel.13351 |