NELF‐A controls Drosophila healthspan by regulating heat‐shock protein‐mediated cellular protection and heterochromatin maintenance

NELF‐mediated pausing of RNA polymerase II (RNAPII) constitutes a crucial step in transcription regulation. However, it remains unclear how control release of RNAPII pausing can affect the epigenome and regulate important aspects of animal physiology like aging. We found that NELF‐A dosage regulates...

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Detalles Bibliográficos
Autores principales: Ngian, Zhen‐Kai, Lin, Wei‐Qi, Ong, Chin‐Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8135010/
https://www.ncbi.nlm.nih.gov/pubmed/33788376
http://dx.doi.org/10.1111/acel.13348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8135010/
https://www.ncbi.nlm.nih.gov/pubmed/33788376
http://dx.doi.org/10.1111/acel.13348

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