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NELF‐A controls Drosophila healthspan by regulating heat‐shock protein‐mediated cellular protection and heterochromatin maintenance
NELF‐mediated pausing of RNA polymerase II (RNAPII) constitutes a crucial step in transcription regulation. However, it remains unclear how control release of RNAPII pausing can affect the epigenome and regulate important aspects of animal physiology like aging. We found that NELF‐A dosage regulates...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8135010/ https://www.ncbi.nlm.nih.gov/pubmed/33788376 http://dx.doi.org/10.1111/acel.13348 |