VPS35 D620N knockin mice recapitulate cardinal features of Parkinson’s disease

D620N mutation in the vacuolar protein sorting 35 ortholog (VPS35) gene causes late‐onset, autosomal dominant familial Parkinson's disease (PD) and contributes to idiopathic PD. However, how D620N mutation leads to PD‐related deficits in vivo remains unclear. In the present study, we thoroughly...

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Detalles Bibliográficos
Autores principales: Niu, Mengyue, Zhao, Fanpeng, Bondelid, Karina, Siedlak, Sandra L., Torres, Sandy, Fujioka, Hisashi, Wang, Wenzhang, Liu, Jun, Zhu, Xiongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8135078/
https://www.ncbi.nlm.nih.gov/pubmed/33745227
http://dx.doi.org/10.1111/acel.13347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8135078/
https://www.ncbi.nlm.nih.gov/pubmed/33745227
http://dx.doi.org/10.1111/acel.13347

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