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Single Amino Acid Mutation of Pyranose 2-Oxidase Results in Increased Specificity for Diabetes Biomarker 1,5-Anhydro-D-Glucitol

Pyranose 2-oxidases catalyze the oxidation of various pyranose sugars at the C2 position. However, their potential application for detecting sugars other than glucose in blood is hindered by relatively high activity towards glucose. In this study, in order to find a mutant enzyme with enhanced speci...

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Detalles Bibliográficos
Autores principales: Fujii, Takahiro, Igarashi, Kiyohiko, Samejima, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Applied Glycoscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8135088/
https://www.ncbi.nlm.nih.gov/pubmed/34354532
http://dx.doi.org/10.5458/jag.jag.JAG-2020_0002