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Interactions among mTORC, AMPK and SIRT: a computational model for cell energy balance and metabolism

BACKGROUND: Cells adapt their metabolism and activities in response to signals from their surroundings, and this ability is essential for their survival in the face of perturbations. In tissues a deficit of these mechanisms is commonly associated with cellular aging and diseases, such as cardiovascu...

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Detalles Bibliográficos
Autores principales: Sadria, Mehrshad, Layton, Anita T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8135154/
https://www.ncbi.nlm.nih.gov/pubmed/34016143
http://dx.doi.org/10.1186/s12964-021-00706-1