Mitochondrial DNA leakage induces odontoblast inflammation via the cGAS-STING pathway

BACKGROUND: Mitochondrial DNA (mtDNA) is a vital driver of inflammation when it leaks from damaged mitochondria into the cytosol. mtDNA stress may contribute to cyclic GMP-AMP synthase (cGAS) stimulator of interferon genes (STING) pathway activation in infectious diseases. Odontoblasts are the first...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Lu, Zhang, Yi-Fei, Yang, Fu-Hua, Mao, Han-Qing, Chen, Zhi, Zhang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136190/
https://www.ncbi.nlm.nih.gov/pubmed/34016129
http://dx.doi.org/10.1186/s12964-021-00738-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136190/
https://www.ncbi.nlm.nih.gov/pubmed/34016129
http://dx.doi.org/10.1186/s12964-021-00738-7

Ejemplares similares