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Neurodegenerative diseases: a hotbed for splicing defects and the potential therapies
Precursor messenger RNA (pre-mRNA) splicing is a fundamental step in eukaryotic gene expression that systematically removes non-coding regions (introns) and ligates coding regions (exons) into a continuous message (mature mRNA). This process is highly regulated and can be highly flexible through a p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136212/ https://www.ncbi.nlm.nih.gov/pubmed/34016162 http://dx.doi.org/10.1186/s40035-021-00240-7 |