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Neurodegenerative diseases: a hotbed for splicing defects and the potential therapies

Precursor messenger RNA (pre-mRNA) splicing is a fundamental step in eukaryotic gene expression that systematically removes non-coding regions (introns) and ligates coding regions (exons) into a continuous message (mature mRNA). This process is highly regulated and can be highly flexible through a p...

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Detalles Bibliográficos
Autores principales: Li, Dunhui, McIntosh, Craig Stewart, Mastaglia, Frank Louis, Wilton, Steve Donald, Aung-Htut, May Thandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136212/
https://www.ncbi.nlm.nih.gov/pubmed/34016162
http://dx.doi.org/10.1186/s40035-021-00240-7