In vivo assessment of a single adenine mutation in 5′UTR of Endothelin-1 gene in paediatric cases with severe pulmonary hypertension: an observational study

OBJECTIVE: Endothelin-1 plays an important role in the pathogenesis of severe pulmonary hypertension. The + 139 ‘A’, adenine insertion variant in 5′UTR of edn1 gene has been reported to be associated with increased expression of Endothelin-1 in vitro. The aim of present study was to explore the asso...

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Detalles Bibliográficos
Autores principales: Kumar, Abhishek, Choudhury, Minati, Batra, Sakshi Dhingra, Sikri, Kriti, Gupta, Anushree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136217/
https://www.ncbi.nlm.nih.gov/pubmed/34011397
http://dx.doi.org/10.1186/s13104-021-05609-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136217/
https://www.ncbi.nlm.nih.gov/pubmed/34011397
http://dx.doi.org/10.1186/s13104-021-05609-5

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