Altered connectivity of the default mode network in cognitively stable adults with Down syndrome: “Accelerated aging” or a prelude to Alzheimer's disease?

INTRODUCTION: Most individuals with Down syndrome (DS) have the neuropathological changes of Alzheimer's disease (AD) by age 40 and will have developed dementia by age 60. Alterations of the intrinsic connectivity of the default mode network (DMN) are associated with AD in the neurotypical popu...

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Detalles Bibliográficos
Autores principales: Rosas, H. Diana, Lewis, Lydia R., Mercaldo, Nathaniel D., Nasr, Shahin, Brickman, Adam M., Siless, Viviana, Yassa, Michael, Sathishkumar, Mithra, Lott, Ira, Schupf, Nicole, Silverman, Wayne, Lai, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136300/
https://www.ncbi.nlm.nih.gov/pubmed/34027014
http://dx.doi.org/10.1002/dad2.12105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136300/
https://www.ncbi.nlm.nih.gov/pubmed/34027014
http://dx.doi.org/10.1002/dad2.12105

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