Adaptive Admixture of HLA Class I Allotypes Enhanced Genetically Determined Strength of Natural Killer Cells in East Asians

Human natural killer (NK) cells are essential for controlling infection, cancer, and fetal development. NK cell functions are modulated by interactions between polymorphic inhibitory killer cell immunoglobulin-like receptors (KIR) and polymorphic HLA-A, -B, and -C ligands expressed on tissue cells....

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Detalles Bibliográficos
Autores principales: Deng, Zhihui, Zhen, Jianxin, Harrison, Genelle F, Zhang, Guobin, Chen, Rui, Sun, Ge, Yu, Qiong, Nemat-Gorgani, Neda, Guethlein, Lisbeth A, He, Liumei, Tang, Mingzhong, Gao, Xiaojiang, Cai, Siqi, Palmer, William H, Shortt, Jonathan A, Gignoux, Christopher R, Carrington, Mary, Zou, Hongyan, Parham, Peter, Hong, Wenxu, Norman, Paul J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136484/
https://www.ncbi.nlm.nih.gov/pubmed/33616658
http://dx.doi.org/10.1093/molbev/msab053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136484/
https://www.ncbi.nlm.nih.gov/pubmed/33616658
http://dx.doi.org/10.1093/molbev/msab053

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