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Reconstruction of Microbial Haplotypes by Integration of Statistical and Physical Linkage in Scaffolding

DNA sequencing technologies provide unprecedented opportunities to analyze within-host evolution of microorganism populations. Often, within-host populations are analyzed via pooled sequencing of the population, which contains multiple individuals or “haplotypes.” However, current next-generation se...

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Detalles Bibliográficos
Autores principales: Cao, Chen, He, Jingni, Mak, Lauren, Perera, Deshan, Kwok, Devin, Wang, Jia, Li, Minghao, Mourier, Tobias, Gavriliuc, Stefan, Greenberg, Matthew, Morrissy, A Sorana, Sycuro, Laura K, Yang, Guang, Jeffares, Daniel C, Long, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136496/
https://www.ncbi.nlm.nih.gov/pubmed/33547786
http://dx.doi.org/10.1093/molbev/msab037