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Reconstruction of Microbial Haplotypes by Integration of Statistical and Physical Linkage in Scaffolding
DNA sequencing technologies provide unprecedented opportunities to analyze within-host evolution of microorganism populations. Often, within-host populations are analyzed via pooled sequencing of the population, which contains multiple individuals or “haplotypes.” However, current next-generation se...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136496/ https://www.ncbi.nlm.nih.gov/pubmed/33547786 http://dx.doi.org/10.1093/molbev/msab037 |